More on an anti-proton research paper

Today I came across an article that comments on the JAMA article by Sheets et al, mentioned in my October 28 post Material Provided by the Radiation Oncologist. This additional paper is

●Reviews in Urology, 2014, 16 (2)

Proton Beam Therapy for Localized Prostate Cancer 101: Basics, Controversies, and Facts, Eric S. Wisenbaugh, MD, et al.

After describing the results published by Sheets et al, the authors commented “However, among the several flaws of this study, the most fundamental was that outcome surrogates (ie, claims for colonoscopy) were used to measure toxicity rates. This would be an imprecise surrogate for any population, but is particularly so in PBT patients…this study should not be used to relay any important morbidity information to inquiring patients.